Side Effects Of HCG Injections For Infertility






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1. What is HCG?

HCG, or Human Chorionic Gonadotropin is usually known as the “pregnancy hormone”. It is the hormone that is released by the placenta, and it is the hormone that is detected by home pregnancy tests. Sometimes, for women who have a hard time conceiving, doctors sometimes prescribe HCG injections. These injections help the ovaries to release the eggs for them to be fertilized. However, there are some common side effects associated with HCG injections.

human -chorionic-gonadotropin-is-known-as-the-pregnancy-hormone

2. Weight Gain

Weight gain is a very common symptom associated with HCG hormone injections. These injections cause edema because they cause fluid retention. Fluid retention makes it seem like you are gaining weight, but the weight gain is really from the fluid. A little bit of weight gain is normal but too much can be a problem and can mean that you need to see your doctor.


3. Ovarian Hyper Stimulation Syndrome (OHSS)

Ovarian Hyper Stimulation Syndrome, also known as OHSS is a complication that sometimes occurs with HCG injections. Experts say that as many as 25 percent of patients that get HCG injections will experience OHSS. OHSS comes in two different forms, a mild form and a more severe form. Twenty five percent of patients will develop the mild form, and it normally goes away in within a week.


The more severe form will require a doctor’s visit. If you develop the mild form of OHSS, you may experience symptoms such as diarrhea, pain in your abdomen, bloating, vomiting and a feeling of tenderness. The more serious version of OHSS may produce such symptoms as breathing problems, severe pain in your abdominal region, discolored urination and others.

4. Depression

Strangely, another side effect of the HCG injections can be depression. This is because of the hormones that are associated with the injections. These feelings are completely normal, and are just an effect of the injections. You might also feel irritated or frustrated, and you might feel like you are on extreme PMS. These feelings will fade away with time, just be patient.


5. Breast Issues

Another common side effect of the HCG hormone injections are breast issues. Your breasts might feel tender and painful. They also might be swollen from time to time. This is also a very normal side effect and many women experience it.


Once your body gets adjusted to the injections, these symptoms should go away. However, if you still have any symptoms after being on the injections for a few days, talk with your doctor in order to make sure that all of your symptom are normal and do not indicate a problem.

Ms. Ledoux began her career as an ObGyn nurse practitioner prior to becoming a practicing midwife in the Santa Cruz community. Working together with ObGyn physicians in her own practice, she has over 20 years experience in women's health, pregnancy and childbirth.
  • giselle

    I have an ovarian cyst & I’ve been trying for 3 years now. What can me & my fiance do for us to get pregnant? What OTC fertility pills should I NOT take? Is there a way for me to manipulate my ovulation days? Since he’s in the military.

    • Dr. Prabha Sahgal, MD

      Common ovarian cysts will not prevent you from getting pregnant and will typically go away on their own within 8-12 weeks. As long as you are having menstrual cycles & ovulating, then you may safely take any type of over-the-counter fertility pills. Ovulation will take place midway through your cycle. While you are unable to manipule the day you ovulate, pinpointing the exact day of ovulation by taking ovulation predictor kits (OPK) and charting your basal body temperatures will help you in timing intercourse.

  • Jewels

    I am 31 n recently married my soulmate. We have been trying repeatedly even doctor appts. We have tried ovulation kits n such n started prenatal vitamins We also have been trying for 8 months n nothing .. I have one child whom is 9 n he has 6 kids n 4 of them r twins … I’m scared cause some years after my son was born I had pre-cancer cells removed n all my yearly paps have been clear n I am sooo confused … I am being treated for continuing BV’s … Uurrgghh which I can’t stand. I’m n need of help n advise.

    • Dr. Prabha Sahgal, MD

      On average, just over 50% of couples will get pregnant within six months, 75% within 9 months. Secondary infertility is common, and usually tied to the mother’s more advanced age. You should be charting your basal body temperatures each month, to really determine when you are ovulating to best time intercourse. Ovulation predictor kits (OPKs) are great, but you need to be consistent and have enough on hand to use until you get the positive test result. Once you have consistently been timing intercourse to the day you ovulate and had up to a year with no pregnancy, that is when it is time to seek advice from your healthcare provider.

  • mollymags

    I’m on day 2 of Conceiveeasy conception pills. no side effects so far. been ttc for 8 months with no luck so we’ll see what happens!  *fingers crossed* I;ve had different tests done and everything looks good so far. Wish me luck!

    • lalalaura

      ***baby dust*** to you!!

    • joleen

       I just ordered yesterday and am on pins and needles waiting for it to get here!

  • lora88

    my preoid only last five to six days when whould i be ovulation
    how many days after

    • PCOSsuccess

      Hey guys! My PCOS prevents me from
      knowing when I ovulate, and even if I am ovulating. If your having
      problems with ovulation and predicting ovulation you should try the
      ConceiveEasy kit. It helps promote ovulation and I also got free
      ovulation tests to help me pinpoint when I ovulate. I hope this helps
      you because it sure helped me. I know that I’m ovulating, I know when
      I’m ovulating, and now I’m just waiting to see if there is a baby
      growing in there. I’ll keep you guys posted. Good Luck to you all!

  • JohnWilder

    I want to know how many months those it really take give me a 100%

  • Carly_Burr

    I really did not think one pill a day would work for me. I really was thinking I was going to need more help then this!! Pregnant!!! I am so happy this worked only 2 months and I am pregnant!! 

  • lisasmith

     Can you become pregnant if you have sexual intercourse on the day of ovulation but did not have sex days prior to ovulation day